Blar i forfatter "Moe, Øystein Kittel"

Viser treff 1-4 av 4

    • Discovery and validation of mucosal TNF expression combined with histological score-a biomarker for personalized treatment in ulcerative colitis 

      Florholmen, Jon; Johnsen, Kay-Martin; Meyer, Renate; Olsen, Trine; Moe, Øystein Kittel; Tandberg, Petter; Gundersen, Mona Dixon; Kvamme, Jan-Magnus; Johnsen, Knut; Løitegård, Terje; Raschpichler, Gabriele; Vold, Cecilia; Sørbye, Sveinung; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-02)
      <i>Background</i> - There are no accurate markers that can predict clinical outcome in ulcerative colitis at time of diagnosis. The aim of this study was to explore a comprehensive data set to identify and validate predictors of clinical outcome in the first year following diagnosis.<p> <p><i>Methods</i> - Treatment naive-patients with ulcerative colitis were included at time of initial diagnosis ...

    • Head to head comparison of two commercial fecal calprotectin kits as predictor of Mayo endoscopic sub-score and mucosal TNF expression in ulcerative colitis 

      Goll, Rasmus; Heitmann, Richard; Moe, Øystein Kittel; Katrine, Carlsen; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-02)
      <i>Background</i> - Fecal calprotectin is widely used to monitor disease activity in patients with inflammatory bowel disease. Multiple commercial kits exist, however, since the analyses are not standardized, these kits cannot be used interchangeably. We aimed to perform a technical evaluation of two kits (Calpro from Calprolab, Norway and Calprest from Eurospital, Italy) and perform a tuning for ...

    • Pharmacodynamic mechanisms behind a refractory state in inflammatory bowel disease 

      Goll, Rasmus; Moe, Øystein Kittel; Johnsen, Kay-Martin; Meyer, Renate Weenås; Friestad, Joachim; Gundersen, Mona Dixon; Kileng, Hege; Johnsen, Knut; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      Background and aims - Biological therapy for inflammatory bowel disease is efficient in many cases but not all. The underlying molecular mechanisms behind non-response to biological therapy in inflammatory bowel disease are poorly described. Therefore, we aimed to characterize the mucosal cytokine transcript profile in non-immunogenic, non-responder patients with adequate trough level.<p> <p>Material ...

    • Prediction of long-term remission in patients following discontinuation of anti-TNF therapy in ulcerative colitis: a 10 year follow up study 

      Johnsen, Kay-Martin; Florholmen, Jon; Moe, Øystein Kittel; Gundersen, Mona Dixon; Beilfuss, Julia; Kileng, Hege; Sørbye, Sveinung; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)
      Background - The long-term outcomes of Ulcerative colitis (UC) after discontinuation of biological therapy are largely unknown. There is also a lack of accurate and validated markers that can predict outcome after withdrawal accurately. The aims of this study were to describe the long-term outcomes in UC patients following cessation of anti-TNF therapy and explore potential biomarkers as an approach ...